Cadherin superfamily
WebCDH17. Cadherin-17 is a protein that in humans is encoded by the CDH17 gene. [5] [6] [7] This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region ... WebE-cadherin, also known as cadherin-1, CDH1 and CD324, is a member of the cadherin superfamily. E-cadherin is widely expressed in epithelial cells. It is a calcium-dependent, transmembrane cell-cell adhesion glycoprotein composed of four extracellular cadherin repeats and a highly conserved cytoplasmic tail region.
Cadherin superfamily
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WebCDH5 - cadherin 5. This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. WebT-cad (T-cadherin), a glycosylphosphatidylinositol-anchored cadherin superfamily member, is expressed widely in the brain and cardiovascular system, and absent, decreased, or even increased, in cancers. Mechanisms controlling T-cad expression are poorly understood. The present study investigated transcriptional regulation of T-cad in …
WebFeb 1, 2009 · Cladogram of organisms for which cadherin superfamily members are analyzed in this review, or for which recently extensive genome sequences have become available. Evolution proceeds from bottom to top and from left to right. Species names are in italics on the right (with two-letter acronyms between brackets). WebCadherins are a superfamily of transmembrane proteins grouped by the presence of one or more cadherin repeats in their extracellular domains. Arrays of these approximately 110 …
WebMar 1, 2001 · CDH13 is an atypical member of the cadherin superfamily located on human chromosome 16q24, which is a recognized region of oncogenic modification for several types of cancer [18, 19].Due to the ... WebNov 29, 2006 · The cadherin superfamily is a group of cell surface receptors that is comprised of more than 100 members. The molecular …
WebDec 29, 2005 · Cadherins are a superfamily of transmembrane proteins grouped by the presence of one or more cadherin repeats in their …
WebMembers of the cadherin superfamily are found in both vertebrates and invertebrates, and include the classical vertebrate cadherins found in cell–cell adherens junctions, the desmogleins and desmocollins of desmosomes, and others of less certain cellular localization. All are type I membrane proteins whose extracellular portion contains ... memo words crosswordWebMoreover, a subfamily of the cadherin superfamily, CNR (c adherin-related n euronal r eceptor) proteins bound to tyrosine kinase Fyn, is localized in synaptic membrane (Kohmura et al. 1998). At least three protocadherin gene subfamilies including the CNR s are derived from an unusual genomic organization similar to that of BCR and TCR gene ... memo twitter elon muskWebProtocadherins (Pcdhs) are the largest mammalian subgroup of the cadherin superfamily of homophilic cell-adhesion proteins. They were discovered by Shintaro Suzuki's group, … memo\\u0027s coffee shopWebCadherin superfamily: general molecular features. At least 80 members of the cadherin superfamily have been shown to be expressed within a single mammalian species; … memo with letterheadWebThis volume enables graduate students and young researchers to learn the basics and gain a comprehensive image of the cadherin superfamily, and experts in the field will easily find various topics of interest in relevant areas of study. Additionally, a list of cadherin-related diseases is included for quick reference to cadherins in human diseases. memo\\u0027s coffee shop west springfieldWebFeb 1, 2009 · This review deals with the large and pleiotropic superfamily of cadherins and its molecular evolution. We compiled literature data and an in-depth phylogenetic … memo with referencesWebA recent crystal structure of the complex of a cadherin extracellular portion and a small molecule inhibitor allowed the identification of a druggable interface, thus providing a … memo writing pattern