Dapagliflozin molecular weight
WebDapagliflozin (BMS-512148) is an orally active, potent and selective renal sodium-dependent glucose cotransporter 2 (SGLT2; SLC5A2) inhibitor (human/rat SGLT2 IC 50 = 1.1/3 nM vs. human/rat SGLT1 IC 50 = 1.39/0.6 μM; R-methyl-D-glucopyranoside (AMG) uptake assay with respective CHO transfectants). WebDapagliflozin is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes.Controlling high blood sugar helps prevent kidney damage, …
Dapagliflozin molecular weight
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WebApr 4, 2024 · Dapagliflozin is a prescription medicine used: along with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes. to reduce the risk of … WebTitle: Dapagliflozin Molecular Formula: C21H25ClO6 Molecular Weight: 408.88 Percent Composition: C 61.69%, H 6.16%, Cl 8.67%, O 23.48% Standard InChI: …
WebIn a randomized, active-controlled, open-label trial, 57 patients with type 2 diabetes and NAFLD were randomized to either the dapagliflozin (5 mg/d) group or the control group. … WebJan 8, 2014 · Dapagliflozin compound with (2s)-1,2-propanediol hydrate / Dapagliflozin propanediol / Dapagliflozin propylene glycolate hydrate External IDs BMS-512148-05 …
WebMar 28, 2024 · Therapy with dapagliflozin reduced HbA1c by 0.9% and body weight by 3.1 kg, mainly attributable to reduction of body water and lean mass. As compared to placebo, dapagliflozin reduced CEC (-6.7 ± 2.4 versus 0.3 ± 1.8%; p = 0.043), but this effect was no longer significant after adjusting for age and BMI. WebAttachment 1: Product information for AusPAR Xigduo XR dapagliflozin (as propanediol monohydrate) / metformin hydrochloride AstraZeneca Pty Ltd PM-2013-01515-1-5 Date of ... Molecular weight: 165.63 . DESCRIPTION Dapagliflozin . Dapagliflozin drug substance is a white to off-white powder, is non-hygroscopic, cryst alline. ...
WebDapagliflozin has good permeability across Caco-2 cell membranes and is a substrate for P-glycoprotein (P-gp) but not a significant P-gp inhibitor. Dapagliflozin is stable in rat, dog, …
Webcapivasertib + CTx CAPItello-290 1st-line metastatic triple negative breast cancer. capivasertib + docetaxel CAPItello-280 mCRPC prostate cancer. capivasertib + fulvestrant + palbociclib CAPItello-292 1st-line triplet in early relapse/ET resistant locally advanced (inoperable) or metastatic breast cancer. how many casinos in californiaWebJun 15, 2024 · Dapagliflozin treatment for 12 weeks is associated with improvement in hepatic fat content, a decrease in visceral fat and bodyweight, enhanced glycemic control, and improved liver biochemistry among T2DM patients with NAFLD. Citing Literature Supporting Information Volume 36, Issue 10 October 2024 Pages 2952-2959 how many cast members died from poltergeistWebThe chemical structure of dapagliflozin propanediol monohydrate is: O HO H Cl O CH. 3. OH HO HO H. 3. C OH H OH. . H. 2. O. CAS Number: 960404-48-2 . Molecular formula: … how many cast in gravityWebJun 14, 2024 · It has a molecular formula C 24 H 33 ClO 8 with molecular weight 408.98. Dapagliflozin is a white to half white crystalline powde r which is soluble in ethanol, methanol, dime thylsulfoxide and ... high school brochure examplesWebDapagliflozin is in a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It lowers blood sugar by causing the kidneys to get rid of more glucose in the … how many casks in cellar stardewWebMolecular Formula C21 H25 Cl O6 Molecular Weight 408.87 API Family Dapagliflozin (2S)-1,2-Propanediol Monohydrate Product Categories API standards, Additional pharmaceutical toxicology reference materials, Mikromol Product Type API ISO 17034 Pack Size: 100 mg 100+ in stock Need More? Estimated dispatch In stock and ready for … high school brochureWebJan 1, 2024 · 1351438-75-9. dapagliflozin propanediol monohydrate. 960404-48-2. Chemsrc provides dapagliflozin (CAS#:461432-26-8) MSDS, density, melting point, … high school broken computer prank